MyBioSource.com's PEP-19 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PEP-19 Antibody was generated using PCP4 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls (PubMed:19106096, PubMed:23204517, PubMed:27876793). For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways (PubMed:21491429).
Subunit Structure: Binds to both calcium-free and calcium-bound calmodulin. The affinity for the calcium-bound form is 50-fold greater.
Similarity: Mostly intrinsically disordered, with residual structure localized to the IQ domain which mediates the interaction with calmodulin. Belongs to the PCP4 family